Every time, the wellness world discovers something that really makes people stop and pay attention. Right now, that’s Urolithin A, which is a powerful compound being called the next big thing in healthy aging and energy support.
In Houston and Sugar Land, more people are turning to Urolithin A supplements for muscle strength and energy. It’s also becoming a favorite in functional medicine programs that are focused on gut health and graceful aging.
In this article, we’ll tell you what it is, how it works, and the benefits you can expect, plus dosage tips and what the latest research says.
What Exactly Is Urolithin A?
Urolithin A is a natural compound your body can make when you eat certain foods, mainly those rich in ellagitannins, like pomegranates, strawberries, raspberries, and walnuts. When these foods reach your gut, bacteria break down their nutrients and create Urolithin A.
But the interesting part is, not everyone’s gut is able to do this. Some people make plenty of it naturally, while others barely produce any at all.
That’s one of the reasons why Urolithin A supplements are becoming so popular. These supplements give everyone a chance to experience the benefits, even if their gut does not have enough power to make it.
Early studies also suggest that Urolithin A may play a role in slowing down your cellular aging and even improving skin health by reducing the effects of sun-related damage. In simple terms, it helps your body repair and renew itself, which is why it’s becoming a favorite thing in longevity and functional medicine circles.

Urolithin A Benefits
1. Boosts Your Energy
Your body runs on tiny power plants called mitochondria. Over time, they can get tired and stop working as well. That’s where Urolithin A comes in. It helps your body clear out old mitochondria and replace them with fresh, healthy ones.
This process, called mitophagy, gives your cells a kind of deep clean. When your cells work better, you feel better stamina and faster recovery.
Studies show Urolithin A supports energy production in older adults, helping them feel more active and alert. For younger people, it may enhance endurance and muscle performance.
2. Promote Your Muscle Strength
Your muscles rely on mitochondria for energy, so keeping them healthy is very crucial. In clinical trials, older adults taking Urolithin A showed better improvements in muscle strength and endurance compared to those who didn’t.
If you feel sore after workouts or get tired during everyday activities, Urolithin A may boost your muscle endurance and recovery.
3. Calm Your Inflammation
Urolithin A helps your immune system work better and keeps low-level inflammation under control. A study showed that after 28 days of taking Urolithin A, people had healthier immune cells that were less tired and more active.
That’s why taking it can help your body stay less inflamed and more resilient overall.
4. Keep Your Brain Sharp and Focused
Your brain needs energy from mitochondria to stay sharp and remember things. Urolithin A helps improve your mitochondrial efficiency, which may protect your brain from age-related issues.
Early studies also show it can reduce brain inflammation linked to memory and thinking. This benefit is still in the very early stages. That’s why researchers are excited about its potential.
How Much Urolithin A Should You Take?
This is one of the questions we get asked the most at Kairos Integrative Care.
For most healthy adults, 250–500 mg per day is commonly recommended by providers. This amount is usually enough to activate your mitophagy and support your mitochondrial health without causing any side effects.
But if your goal is performance or anti-aging, some studies use up to 1000 mg per day. Human studies also back this approach. For example, a 2022 trial in older adults gave 1000 mg/day for four months and saw improvements in muscle endurance and mitochondrial function.
However, the right dosage for you depends on:
- Your gut health
- Your age and mitochondrial health
- Your overall metabolic status
That’s why we always recommend doing functional testing first. It is best to check your gut microbiome and mitochondrial health before starting this supplement.
We recommend you start with a lower dose, around 250–500 mg daily, and gradually increase up to 1000 mg as your body tolerates it. Always consult a healthcare provider, especially if you’re using other metabolic supplements.

Is Urolithin A Safe?
Yes, based on current research, Urolithin A is generally considered safe. Human studies show it is well-tolerated, with no serious side effects.
Some people may see side effects, such as:
- Bloating
- Nausea
- Diarrhea
- Headache
- Back Pain
- Occasional Muscle ache
These side effects are usually temporary but can be uncomfortable..It’s important to remember this supplement is new and its long-term studies are still limited.
It is generally safe for short-term usage, but scientists are still learning about its long-term effects. That’s why we recommend following a guided plan under the supervision of a healthcare provider.
Who Can Benefit and When?
At our functional medicine clinics in Houston and Sugar Land, we often consider Urolithin A for:
- Middle-aged clients feeling low energy or slow recovery
- People whose gut doesn’t convert ellagitannins well, resulting in low Urolithin A production
- Athletes and active individuals
- Older Adults
- Anti-aging
We focus on the basics first and address your deeper issues like poor sleep, stress, low thyroid, nutrient gaps, or gut inflammation, and then add Urolithin A for much better results, if needed.
Final Thought
Urolithin A is one of the most promising compounds in healthy aging. But remember that it’s not a shortcut. The best results come when you combine it with gut health, proper nutrients, good sleep, and stress management.
At Kairos Integrative Care in Sugar Land and Houston, Lola, one of our nurse practitioners, takes a holistic approach to gut repair and metabolic health. She can guide you through functional testing and create a personalized mitochondrial support plan that includes or prepares your body for Urolithin A.
We see patients from Houston, Sugar Land, Richmond, and nearby areas (77046 & 77478), and accept major insurance plans including Blue Cross, Aetna, Ambetter, Cigna, and more.
You can easily book an appointment in person or via telemedicine to start your plan safely and effectively.


